The detailed technical description of is project is:
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PDF --> text --> text-to-speech --> audio --> saved audio file.
There is existing software for each stage that I would integrate. Adobe has an Acrobat SDK, which can extract text from a PDF. The text can be converted to speech with the Microsoft text-to-speech software or maybe even Jaws. The generated speech can be played immediately or saved to file (WAV or Mp3 format). The different components can be combined using Microsoft tools, such as Visual Basic or Visual Studio C++.
PDF 2 text
An Adobe SDK provides a programmable interface to the Adobe Acrobat Reader and Abode Acrobat (the full version). The SDK should provide access to the text of the PDF. There are other solutions on the web to access text from pdf. Here are some solutions.
Text-to-speechIeee Format Generator
Ieee Pdf Express Format Check
Microsoft provides free text-to-speech software. I imagine possible enhancements to simply reading the text with one voice. The voice could change from a man's voice to a woman's voice when reading titles, italics, or other outstanding text.Convert Reference To Ieee Format
Save speech to audio file
The MS text-to-speech generates the audio and can also store the audio to a WAV file. I am sure code exists to convert the WAV to mp3. Once in Mp3, I could imagine downloading the audio to an MP3 player and listening to the PDF paper while walking outside, riding the bus, or in the car.